Treatment-induced mucositis in oncology
Jasiewicz, Francis Qurban, Zeeshan Hughes, Christopher
Jasiewicz, Francis
Qurban, Zeeshan
Hughes, Christopher
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Abstract
Almost all cancer therapies lead to a wide array of side effects, owing to the disruption of normal physiological processes and alteration of immunological responses. Of these, mucositis is one of the most commonly encountered side effects, presenting in about 20-40% of all patients receiving chemotherapy and 80% of those being treated with radiotherapy for head and neck malignancies. This article provides a brief introduction and comprehensive overview of the various treatment modalities used in managing this complication. The key to management is a multidisciplinary approach, revolving around pain control, oral hygiene, nutritional support and management of superimposed infection. The scarcity of therapeutic options for prevention or treatment of mucositis has resulted in clinical difficulty in controlling it, which, in turn, seriously affects the patient's quality of life and cancer management, contributing to patient morbidity and mortality.
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Date
2022
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Article
Citation
Jasiewicz F, Qurban Z, Hughes C. Treatment-induced mucositis in oncology. British journal of hospital medicine (London, England : 2005). 2022 Sep 2;83(9):1-8. PubMed PMID: 36193926. Epub 2022/10/05. eng.