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Malignant melanoma in families of children with osteosarcoma, chondrosarcoma, and adrenal cortical carcinoma.

Hartley, Ann L
Birch, Jillian M
Marsden, Henry B
Harris, Martin
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Abstract
Seven cases of malignant melanoma in the close relatives of children with osteosarcoma and chondrosarcoma are described. The association between certain childhood malignancies (adrenal cortical carcinoma, osteosarcoma, chondrosarcoma, retinoblastoma) and malignant melanoma is discussed and it is proposed that in certain families malignant melanoma may be another manifestation of the same gene defect which results in susceptibility to tumours characteristic of the SBLA cancer family syndrome.
Description
Date
1987-11
Publisher
Keywords
Adrenal Cortex Cancer
Bone Cancer
Skin Cancer
Type
Article
Citation
Malignant melanoma in families of children with osteosarcoma, chondrosarcoma, and adrenal cortical carcinoma. 1987, 24 (11):664-8 J. Med. Genet.
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