Acromegaly due to production of a growth hormone releasing factor by a bronchial carcinoid tumor.
Shalet, Stephen M Beardwell, Colin G MacFarlane, I A Ellison, M Norman, C Rees, L Hughes, M
Shalet, Stephen M
Beardwell, Colin G
MacFarlane, I A
Ellison, M
Norman, C
Rees, L
Hughes, M
Citations
Altmetric:
Abstract
We have studied growth hormone production in a patient with a bronchial carcinoid and acromegaly. The absence of growth hormone from the carcinoid tumour was demonstrated by extraction, cell culture and immunoperosidase techniques. Using a linked perfusion culture system, effluent from the bronchial carcinoid tumour culture stimulated a rapid release of growth hormone from a rat pituitary monolayer. This is the first time evidence of growth hormone releasing activity by a bronchial carcinoid has been demonstrated in a production.
Description
Date
1979-01
Publisher
Collections
Keywords
Type
Article
Citation
Acromegaly due to production of a growth hormone releasing factor by a bronchial carcinoid tumor. 1979, 10 (1):61-7 Clin Endocrinol