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Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the International Watch & Wait Database (IWWD): an international multicentre registry study.
van der Valk, M Hilling, D Bastiaannet, E Meershoek-Klein Kranenbarg, E Beets, G Figueiredo, N Habr-Gama, A Perez, R Van de Velde, C
van der Valk, M
Hilling, D
Bastiaannet, E
Meershoek-Klein Kranenbarg, E
Beets, G
Figueiredo, N
Habr-Gama, A
Perez, R
Van de Velde, C
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Abstract
The strategy of watch and wait (W&W) in patients with rectal cancer who achieve a complete clinical response (cCR) after neoadjuvant therapy is new and offers an opportunity for patients to avoid major resection surgery. However, evidence is based on small-to-moderate sized series from specialist centres. The International Watch & Wait Database (IWWD) aims to describe the outcome of the W&W strategy in a large-scale registry of pooled individual patient data. We report the results of a descriptive analysis after inclusion of more than 1000 patients in the registry.
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2018-06-23
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Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the International Watch & Wait Database (IWWD): an international multicentre registry study. 2018, 391(10139): 2537-2545 Lancet