Investigation of the possible involvement of ketonic derivatives of polycyclic hydrocarbons in hydrocarbon carcinogenesis.
Dipple, A Levy, L S Iype, P Thomas
Dipple, A
Levy, L S
Iype, P Thomas
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Abstract
5,6-Dihydro-5-oxo-7,12-dimethylbenz(a)anthracene and 5,6-dihydro-6-oxo-7,12-dimethylbenz(a)anthracene are described. These compounds, which are isomeric with 7,12-dimethylbenz(a)anthracene-5,6-oxide (the K-region epoxide), were inactive in tests for tumor-initiating activity in mouse skin and tumor production in the s.c. tissue of the mouse.
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1975-03
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Investigation of the possible involvement of ketonic derivatives of polycyclic hydrocarbons in hydrocarbon carcinogenesis. 1975, 35 (3):652-7 Cancer Res.