Management of a New Isolated Metastasis during Sunitinib Treatment in Renal Cell Carcinoma Patients: A Lesson from Two Cases.
Shablak, Alaaeldin O'Dwyer, Jackie F Hawkins, Robert E Board, Ruth E
Shablak, Alaaeldin
O'Dwyer, Jackie F
Hawkins, Robert E
Board, Ruth E
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Abstract
Metastatic renal cell carcinoma (mRCC) is a difficult to treat malignancy and currently Sunitinib is a standard of care first-line therapy. A new metastasis during the treatment is considered a sign of drug failure and alternative therapeutic methods should be tried. Here, we report 2 cases of newly diagnosed isolated metastasis during Sunitinib treatment of mRCC patients. Our management plan included local palliative therapy to the lesion followed by recommencing of Sunitinib. This resulted in a good symptomatic relief locally as well as good overall control of the disease.
Description
Date
2010-12-02
Publisher
Collections
Keywords
Renal Cell Carcinoma
Sunitinib Treatment
Palliative Therapy
Sunitinib Treatment
Palliative Therapy
Type
Article
Citation
Management of a New Isolated Metastasis during Sunitinib Treatment in Renal Cell Carcinoma Patients: A Lesson from Two Cases. 2010: Urol Int