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Regorafenib plus modified FOLFOX6 as first-line treatment of metastatic colorectal cancer: A phase II trial.
Argilés, G ; Saunders, Mark P ; Rivera, F ; Sobrero, A ; Benson, A ; Guillén Ponce, C ; Cascinu, S ; Van Cutsem, E ; Macpherson, I ; Strumberg, D ... show 7 more
Argilés, G
Saunders, Mark P
Rivera, F
Sobrero, A
Benson, A
Guillén Ponce, C
Cascinu, S
Van Cutsem, E
Macpherson, I
Strumberg, D
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Abstract
The oral multikinase inhibitor regorafenib improves overall survival (OS) in patients with metastatic colorectal cancer (CRC) for which all standard treatments have failed. This study investigated regorafenib plus modified FOLFOX (mFOLFOX6) as first-line treatment of metastatic CRC.
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2015-03-24
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Regorafenib plus modified FOLFOX6 as first-line treatment of metastatic colorectal cancer: A phase II trial. 2015: Eur J Cancer