Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the Genomic Health recurrence score in early breast cancer.
Cuzick, J Dowsett, M Pineda, S Wale, C Salter, J Quinn, E Zabaglo, L Mallon, E Green, A R Ellis, I O
Cuzick, J
Dowsett, M
Pineda, S
Wale, C
Salter, J
Quinn, E
Zabaglo, L
Mallon, E
Green, A R
Ellis, I O
Citations
Altmetric:
Abstract
We recently reported that the mRNA-based, 21-gene Genomic Health recurrence score (GHI-RS) provided additional prognostic information regarding distant recurrence beyond that obtained from classical clinicopathologic factors (age, nodal status, tumor size, grade, endocrine treatment) in women with early breast cancer, confirming earlier reports. The aim of this article is to determine how much of this information is contained in standard immunohistochemical (IHC) markers.
Description
Date
2011-11-10
Publisher
Collections
Keywords
Type
Article
Citation
Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the Genomic Health recurrence score in early breast cancer. 2011, 29 (32):4273-8 J Clin Oncol