Phase I trials in paediatric oncology--the European perspective. The New Agents Group of the United Kingdom Childrens Cancer Study Group.
Estlin, E J Ablett, S Newell, D R Lewis, I J Lashford, Linda S Pearson, A D
Estlin, E J
Ablett, S
Newell, D R
Lewis, I J
Lashford, Linda S
Pearson, A D
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Abstract
The current recommendations for Phase I trials should allow more confident interpretation of the toxicity and efficacy of new agents by providing a framework for multicentre and international co-operation. An overview of the aims and designs of Phase I trials is presented, along with a summary of current and recently published United Kingdom Childrens Cancer Study Group Phase I trials, and a discussion of some of the difficulties faced in the methodology and evaluation of Phase I studies in children.
Description
Date
1996
Publisher
Collections
Keywords
Cancer
Type
Article
Citation
Phase I trials in paediatric oncology--the European perspective. The New Agents Group of the United Kingdom Childrens Cancer Study Group. 1996, 14 (1):23-32 Invest New Drugs