The prognostic value of dynamic contrast-enhanced MRI contrast agent transfer constant K(trans) in cervical cancer is explained by plasma flow rather than vessel permeability.
Dickie, Ben R ; Rose, C ; Kershaw, Lucy E ; Withey, S ; Carrington, Bernadette M ; Davidson, Susan E ; Hutchison, G ; West, Catharine M L
Dickie, Ben R
Rose, C
Kershaw, Lucy E
Withey, S
Carrington, Bernadette M
Davidson, Susan E
Hutchison, G
West, Catharine M L
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Abstract
The microvascular contrast agent transfer constant K(trans) has shown prognostic value in cervical cancer patients treated with chemoradiotherapy. This study aims to determine whether this is explained by the contribution to K(trans) of plasma flow (Fp), vessel permeability surface-area product (PS), or a combination of both.
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2017-04-27
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The prognostic value of dynamic contrast-enhanced MRI contrast agent transfer constant K(trans) in cervical cancer is explained by plasma flow rather than vessel permeability. 2017 Br J Cancer