Scoring of treatment-related late effects in prostate cancer.
Livsey, Jacqueline E Routledge, Jacqueline A Burns, Meriel P Swindell, Ric Davidson, Susan E Logue, John P Wylie, James P
Livsey, Jacqueline E
Routledge, Jacqueline A
Burns, Meriel P
Swindell, Ric
Davidson, Susan E
Logue, John P
Wylie, James P
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Abstract
BACKGROUND AND PURPOSE: To assess the correlation between different general and organ specific quality of life and morbidity scoring methods in a cohort of men treated with radical radiotherapy for prostate cancer. MATERIALS AND METHODS: Men who had been treated with radical radiotherapy (50 Gy in 16 fractions over 21 days) for localized prostate cancer more than 3 years previously and who had no evidence of recurrent disease were invited to take part in the study. A total of 101 of 135 invited patients agreed and completed LENT/SOMA, UCLA Prostate Cancer Index, and 36 item RAND Health survey questionnaires. RESULTS: The patients had comparable results with other published series with respect to the UCLA and SF-36 indices. There was significant correlation between the corresponding parts of the UCLA and LENT/SOMA scales (P<0.0005). However, for the same symptoms, a patient tended to score lower (worse) on the UCLA scale in comparison to LENT/SOMA. The relationship between the average LENT/SOMA score and maximum score was also not straightforward with each set of data revealing different information. CONCLUSIONS: The LENT/SOMA questions were, in the main, more wide-ranging and informative than the UCLA index. It is helpful to give both the overall and maximum LENT/SOMA scores to most efficiently use all of the data. There may need to be a further LENT/SOMA question to allow both symptoms of tenesmus and faecal urgency to be fully addressed.
Description
Date
2002-11
Publisher
Collections
Keywords
Prostatic Cancer
Type
Article
Citation
Scoring of treatment-related late effects in prostate cancer. 2002, 65 (2):109-21 Radiother Oncol