Tissue polypeptide antigen (TPA): usefulness in urological neoplasia.
Costello, C B Kumar, S
Costello, C B
Kumar, S
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Abstract
Urine and serum samples from a group of 359 individuals were studied in order to evaluate the usefulness of TPA in patients with urological cancers. Serum was taken from 110 people at 12 noon (S1), 5 pm (S2), and 8 am the following day (S3), while urine samples were collected from 73 individuals over three time intervals: 8 am to 12 noon (U1), 12 noon to 5 pm (U2), and 5 pm to 8 am the following morning (U3). In addition, there were 24-hour urine samples from 176 persons. TPA concentrations in S1, S2, or S3 were not correlated with the presence of a tumor. In contrast, good correlation was observed between TPA concentrations in U1, U2, or U3 and disease status and an even better correlation existed between TPA in 24-hour urine samples and disease status. It is proposed that the judicious use of 24-hour urinary TPA levels should prove valuable in monitoring the course of urological cancers.
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Affiliation
Description
Date
1986
Publisher
Collections
Keywords
Cancer Antigens
Urologic Cancer
Urologic Cancer
Type
Article
Citation
Tissue polypeptide antigen (TPA): usefulness in urological neoplasia., 6 (4):713-6 Anticancer Res