Recent developments in the therapy of acromegaly.
Paisley, Angela N Trainer, Peter J
Paisley, Angela N
Trainer, Peter J
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Abstract
Acromegaly, a condition due to growth hormone hypersecretion usually from a benign pituitary tumour, is associated with significant morbidity and mortality. Disease control leads to normalisation of life expectancy with a reduction in signs and symptoms. Treatment modalities include surgery, radiotherapy and medical management. Surgery is the primary treatment in most of the patients, with success rates of 61-91% reported for those with microadenomas who are operated on by a specialist pituitary surgeon; however, most patients have macroadenomas and, although benefiting from surgery, are not cured and require additional medical therapy. This review will focus on emerging concepts in the medical treatment of acromegaly.
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2006-03
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Recent developments in the therapy of acromegaly. 2006, 15 (3):251-6 Expert Opin Investig Drugs