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Angiogenic factor from synovial fluid resembling that from tumours.
Brown, R A Weiss, J B Tomlinson, I W Phillips, Paul Kumar, Shant
Brown, R A
Weiss, J B
Tomlinson, I W
Phillips, Paul
Kumar, Shant
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Abstract
Synovial fluids from 2 of 2 patients with osteoarthritis, 2 of 8 with rheumatoid arthritis, and 2 of 2 with ankylosing spondylitis contained a low-molecular-weight angiogenesis factor apparently identical with that derived from tumours. The amount of factor present was highest in patients with osteoarthritis, 2 patients with psoriatic arthropathy gave negative results. It is suggested that angiogenesis factor is involved, directly or indirectly, in the production of synovial exudate.
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Date
1980-03-29
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Article
Citation
Angiogenic factor from synovial fluid resembling that from tumours. 1980, 1 (8170):682-5 Lancet