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Proton beam therapy - the challenges of delivering high-quality evidence of clinical benefit.
Amos, R Bulbeck, H Burnet, Neil G Crellin, A Eaton, D Evans, P Hall, E Hawkins, M
Amos, R
Bulbeck, H
Burnet, Neil G
Crellin, A
Eaton, D
Evans, P
Hall, E
Hawkins, M
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Abstract
The use of proton beam therapy (PBT) offers the opportunity to improve greater conformality of radiotherapy treatment delivery in some patients. However, it is associated with a high capital cost and the need to build new dedicated facilities. We discuss how the global radiotherapy community can respond to the challenge of producing high-quality evidence of clinical benefit from PBT in adult patients. In the UK, the National Cancer Research Institute-funded Clinical and Radiotherapy Translational group has established the PBT Clinical Trial Strategy Group. An eight-point framework is described that can assist the development and delivery of high-quality clinical trials.
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Date
2018-05
Publisher
Collections
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Article
Citation
Proton beam therapy - the challenges of delivering high-quality evidence of clinical benefit. 2018, 30(5): 280-284 Clin Oncol