Somatic glypican 3 (GPC3) mutations in Wilms' tumour.
White, Gavin R M Kelsey, Anna M Varley, Jennifer Birch, Jillian M
White, Gavin R M
Kelsey, Anna M
Varley, Jennifer
Birch, Jillian M
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Abstract
Tumour and normal tissue from 41 male cases of Wilms' tumour were screened to determine the presence of sequence variants in the glypican 3 (GPC3) gene. Two non-conservative single base changes were present in tumour tissue only. These findings imply a possible role for GPC3 in Wilms' tumour development.
Description
Date
2002-06-17
Publisher
Collections
Keywords
Kidney Cancer
Renal Cancer
Wilms Tumour
Renal Cancer
Wilms Tumour
Type
Article
Citation
Somatic glypican 3 (GPC3) mutations in Wilms' tumour. 2002, 86 (12):1920-2 Br. J. Cancer