Radiotherapy in the control of bleeding from primary and secondary lung tumours
Gaito, Simona Hughes, Christopher Woolf, David K Radhakrishna, Ganesh
Gaito, Simona
Hughes, Christopher
Woolf, David K
Radhakrishna, Ganesh
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Abstract
This literature review clarifies the role of radiotherapy in the management of low-volume haemoptysis. Embase and Medline were interrogated, and PRISMA guidelines were then used to select relevant articles. Seventy-eight articles were considered relevant and manually reviewed. The evidence suggests that external beam radiotherapy is more effective than endobronchial brachytherapy at controlling low-volume haemoptysis. There is no evidence to recommend a combination of the two techniques. Different doses and fractionations appear equally effective, with a potential survival advantage of higher dose regimens for fitter patients. Palliative radiotherapy is effective at controlling low-volume haemoptysis. External beam radiotherapy is the first-line treatment, with endobronchial brachytherapy recommended following external beam radiotherapy failure. Choice of dose and fractionation should take into account the patient's performance status.
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Date
2019
Publisher
Collections
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Type
Article
Citation
Gaito S, Hughes C, Woolf D, Radhakrishna G. Radiotherapy in the control of bleeding from primary and secondary lung tumours. Br J Hosp Med (Lond). 2019 Apr 2;80(4):211-5.