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Inter-comparison of quantitative imaging of lutetium-177 (177Lu) in European hospitals.
Wevrett, J Fenwick, A Scuffham, J Johansson, L Gear, J Schlögl, S Segbers, M Sjögreen-Gleisner, K Solný, P Lassmann, M
Wevrett, J
Fenwick, A
Scuffham, J
Johansson, L
Gear, J
Schlögl, S
Segbers, M
Sjögreen-Gleisner, K
Solný, P
Lassmann, M
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Abstract
This inter-comparison exercise was performed to demonstrate the variability of quantitative SPECT/CT imaging for lutetium-177 (177Lu) in current clinical practice. Our aim was to assess the feasibility of using international inter-comparison exercises as a means to ensure consistency between clinical sites whilst enabling the sites to use their own choice of quantitative imaging protocols, specific to their systems. Dual-compartment concentric spherical sources of accurately known activity concentrations were prepared and sent to seven European clinical sites. The site staff were not aware of the true volumes or activity within the sources-they performed SPECT/CT imaging of the source, positioned within a water-filled phantom, using their own choice of parameters and reported their estimate of the activities within the source.
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2018-08-02
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Inter-comparison of quantitative imaging of lutetium-177 (177Lu) in European hospitals. 2018, 5(1): 17 EJNMMI Phys