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Impact of skeletal complications on patients' quality of life, mobility, and functional independence.

Costa, Luis
Badia, Xavier
Chow, Edward
Lipton, Allan
Wardley, Andrew M
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Abstract
INTRODUCTION: Skeletal-related events (SREs) from malignant bone disease cause considerable morbidity and can dramatically reduce patients' quality of life. DISCUSSION: Pathologic fractures often require surgical intervention and palliative radiotherapy. Thus, patients suffer impaired mobility, loss of functional independence, and diminished health-related quality of life (HRQOL). Bisphosphonates can delay the onset and reduce the incidence of SREs and have become the standard of care for the treatment of malignant bone disease; however, minimal information on the effects of bisphosphonate treatment on HRQOL is available. Targeted HRQOL assessments for patients with malignant bone disease are currently under development and are discussed herein.
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Date
2008-08
Publisher
Keywords
Bone Metastases
Bone Pain
Breast Cancer
Prostate Cancer
Zoledronic Acid
Type
Article
Citation
Impact of skeletal complications on patients' quality of life, mobility, and functional independence. 2008, 16 (8):879-89 Support Care Cancer
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