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Novel therapeutic strategies for recurrent SCLC

Moliner, Laura
Zhang, B.
Lamberti, G.
Ardizzoni, A.
Byers, L. A.
Califano, Raffaele
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Abstract
Therapeutic options for patients with relapsed SCLC are limited, and the prognosis in this setting remains poor. While clinical outcomes for frontline treatment have modestly improved with the introduction of immunotherapy, treatment in the second-line setting persists almost unchanged. In this review, current treatment options and recent advances in molecular biology are described. Emerging therapeutic options in this setting, and potential strategies to improve clinical outcomes of these patients are also addressed.
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Date
2023
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Article
Citation
Moliner L, Zhang B, Lamberti G, Ardizzoni A, Byers LA, Califano R. Novel therapeutic strategies for recurrent SCLC. Crit Rev Oncol Hematol. 2023 Jun;186:104017. PubMed PMID: 37150311. Epub 2023/05/08. eng.
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