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Alveolar rhabdomyosarcoma with del(13q14).
Harrison, Christine J Johnson, P R Yin, J A Bhavnani, M
Harrison, Christine J
Johnson, P R
Yin, J A
Bhavnani, M
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Abstract
We report a case of disseminated alveolar rhabdomyosarcoma, where chromosome analysis showed a deletion of chromosome 13(q14). This breakpoint is involved in the t(2;13)(q37;q14) previously reported in cases of rhabdomyosarcoma, but this is the first reported case in whom this deletion occurs without involvement of chromosome 2. The possible oncogenic role of the retinoblastoma (RB1) gene located at the breakpoint is discussed.
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Date
1991-09
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Article
Citation
Alveolar rhabdomyosarcoma with del(13q14). 1991, 55 (2):257-9 Cancer Genet. Cytogenet