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Radiotherapy for small-cell lung cancer-Where are we heading?

Bayman, Neil A
Sheikh, Hamid Y
Kularatne, B
Lorigan, Paul C
Blackhall, Fiona H
Thatcher, Nick
Faivre-Finn, Corinne
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Abstract
Radiotherapy has an established role in the management of limited-disease small-cell lung cancer. However, essential questions related to the optimisation of thoracic radiotherapy remain unanswered including (i) optimal total dose, (ii) fractionation, (iii) timing and sequencing of radiation, (iv) volume of irradiation, and (v) concurrent chemotherapy combinations. The role of thoracic radiotherapy for extensive-disease small-cell lung cancer is more poorly understood but evidence suggests radiotherapy may have an important role in this setting. This review highlights the need for well-designed multi-national trials aimed at the optimisation and standardisation of radiotherapy for SCLC.
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Date
2009-03
Publisher
Keywords
Small-Cell Lung Cancer
Radiotherapy
Thoracic Radiotherapy
Type
Article
Citation
Radiotherapy for small-cell lung cancer-Where are we heading? 2009, 63 (3):307-14 Lung Cancer
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