Expression of 20 alpha-hydroxysteroid dehydrogenase in nonlymphoid hemopoietic cell lines.
Garland, John M Lanotte, Michael Dexter, T Michael
Garland, John M
Lanotte, Michael
Dexter, T Michael
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Abstract
Expression of 20 alpha-hydroxysteroid dehydrogenase (20 alpha-SDH), a putative T cell marker, has been examined in a number of nonlymphoid hemopoietic cell lines. Both promyelocytic and stromal bone marrow lines expressed significant 20 alpha-SDH activity which was not correlated with virus infection or growth rate. 20 alpha-SDH therefore is not a unique marker for T cells in hemopoietic tissues. This result is discussed in relationship to the action of the newly proposed interleukin 3.
Description
Date
1982-04
Publisher
Collections
Keywords
Haematopoietic Stem Cells
Acute Myeloid Leukemia
Acute Myeloid Leukemia
Type
Article
Citation
Expression of 20 alpha-hydroxysteroid dehydrogenase in nonlymphoid hemopoietic cell lines. 1982, 12 (4):332-6 Eur J Immunol