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Watch-and-wait approach versus surgical resection after chemoradiotherapy for patients with rectal cancer (the OnCoRe project): a propensity-score matched cohort analysis.
Malcomson, L Emsley, R Gollins, S Maw, A Myint, A Rooney, P Susnerwala, S Blower, Anthony Saunders, Mark P
Malcomson, L
Emsley, R
Gollins, S
Maw, A
Myint, A
Rooney, P
Susnerwala, S
Blower, Anthony
Saunders, Mark P
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Abstract
Induction of a clinical complete response with chemoradiotherapy, followed by observation via a watch-and-wait approach, has emerged as a management option for patients with rectal cancer. We aimed to address the shortage of evidence regarding the safety of the watch-and-wait approach by comparing oncological outcomes between patients managed by watch and wait who achieved a clinical complete response and those who had surgical resection (standard care).
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2015-12-16
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Watch-and-wait approach versus surgical resection after chemoradiotherapy for patients with rectal cancer (the OnCoRe project): a propensity-score matched cohort analysis. 2015: Lancet Oncol