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Validation of PET data resampling methods to simulate lower injected doses on a multimodality PET-MR scanner

Rodriguez, J. A.
Deller, T. W.
Matthews, J. C.
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Abstract
Aim/Introduction: PET data resampling techniques [1,2] can be used to predict image quality changes with the reduced injected activities or reducing acquisition times using existing full-dose PET data. Methods to resample PET data acquired on the multimodality GE Signa PET-MR scanner has been developed and validated using scanner manufacture ofine reconstruction tools. Materials and Methods: A Flangeless Esser-PET-phantom™ containing a series of cold rods of varying diameters and refllable cylindrical inserts of varying diameters of 8, 12, 16, and 25(x3)mm and one solid cylinder made of Tefon (25mm diameter) was scanned for 60 min with a total of 40 MBq of fuorine-18 at the start of scan and a contrast ratio of 4:1 in “hot cylinders” to background. Resampling of PET projection time-of-fight (TOF) data (10 replications) was performed using random resampling of a Poisson distribution (Matlab function “poissrnd”) at diferent resampling fractions (RF): RF
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Date
2021
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Meetings and Proceedings
Citation
Rodriguez JA, Deller TW, Matthews JC. Validation of PET data resampling methods to simulate lower injected doses on a multimodality PET-MR scanner. Eur J Nucl Med Mol Imaging. 2021;48(SUPPL 1):S497-S.
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