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Molecular mechanisms of metastasis in prostate cancer.

Clarke, Noel W
Hart, Claire A
Brown, Michael D
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Abstract
Prostate cancer (PCa) preferentially metastasizes to the bone marrow stroma of the axial skeleton. This activity is the principal cause of PCa morbidity and mortality. The exact mechanism of PCa metastasis is currently unknown, although considerable progress has been made in determining the key players in this process. In this review, we present the current understanding of the molecular processes driving PCa metastasis to the bone.Asian Journal of Andrology (2009) 11: 57-67. doi: 10.1038/aja.2008.29; published online 1 December 2008.
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Date
2009-01
Publisher
Keywords
Bone
Bone Marrow Stroma
Metastasis
Prostate Cancer
Type
Article
Citation
Molecular mechanisms of metastasis in prostate cancer. 2009, 11 (1):57-67 Asian J. Androl.
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