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Power surge: supporting cells "fuel" cancer cell mitochondria.
Martinez-Outschoorn, U Sotgia, Federica Lisanti, Michael P
Martinez-Outschoorn, U
Sotgia, Federica
Lisanti, Michael P
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Abstract
An emerging paradigm in tumor metabolism is that catabolism in host cells "fuels" the anabolic growth of cancer cells via energy transfer. A study in Nature Medicine (Nieman et al., 2011) supports this; they show that triglyceride catabolism in adipocytes drives ovarian cancer metastasis by providing fatty acids as mitochondrial fuels.
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Date
2012-01-04
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Article
Citation
Power surge: supporting cells "fuel" cancer cell mitochondria. 2012, 15 (1):4-5 Cell Metab