Life expectancy in hereditary cancer predisposing diseases: an observational study.
Wilding, A Ingham, S L Lalloo, F Clancy, T Huson, S M Moran, Anthony Evans, D Gareth R Evans, D Gareth R
Wilding, A
Ingham, S L
Lalloo, F
Clancy, T
Huson, S M
Moran, Anthony
Evans, D Gareth R
Evans, D Gareth R
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Abstract
Neurofibromatosis 1 (NF1), neurofibromatosis 2 (NF2), familial adenomatous polyposis (FAP), von Hippel-Lindau syndrome (VHL), and Gorlin syndrome (GS) are single gene diseases that predispose to early onset tumours. Few studies have assessed the effect of these diseases on life expectancy. This study's aim was to assess this effect, and to test the hypothesis that genetic registers increase survival.
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Date
2012-04
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Article
Citation
Life expectancy in hereditary cancer predisposing diseases: an observational study. 2012, 49 (4):264-9 J Med Genet