Scavenger receptor class B type I regulates cellular cholesterol metabolism and cell signaling associated with breast cancer development.
Danilo, C Gutierrez-Pajares, J Mainieri, M Mercier, I Lisanti, Michael P Frank, P
Danilo, C
Gutierrez-Pajares, J
Mainieri, M
Mercier, I
Lisanti, Michael P
Frank, P
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Abstract
Previous studies have identified cholesterol as an important regulator of breast cancer development. High-density lipoprotein (HDL) and its cellular receptor, the scavenger receptor class B type I (SR-BI) have both been implicated in the regulation of cellular cholesterol homeostasis, but their functions in cancer remain to be established.
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2013
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Scavenger receptor class B type I regulates cellular cholesterol metabolism and cell signaling associated with breast cancer development. 2013, 15 (5):R87 Breast Cancer Res