Cytotoxicity of L-canavanine in vitro.
Naha, P M
Naha, P M
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Abstract
Cytotoxicity of L-canavanive, a structural analogue of L-arginine, was tested by means of (1) inhibition of DNA synthesis in Balb/c-3T3 cell line and (2) inhibition of mitosis in peripheral blood lymphocytes in culture. The cytostatic nature of inhibition caused by L-canavanine was indicated by the complete recovery of cells after withdrawal of the drug.
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1981
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Cytotoxicity of L-canavanine in vitro. 1981, 1 (5):275-7 Anticancer Res.