First-in-human pharmacokinetic and pharmacodynamic study of the dual m-TORC 1/2 inhibitor, AZD2014.
Basu, B Puglisi, M Greystoke, Alastair Ong, M Burke, W Cavallin, M Bigley, G Womack, C Harrington, E
Basu, B
Puglisi, M
Greystoke, Alastair
Ong, M
Burke, W
Cavallin, M
Bigley, G
Womack, C
Harrington, E
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Abstract
AZD2014 is a novel, oral, m-TORC 1/2 inhibitor which has shown in-vitro and in-vivo efficacy across a range of preclinical human cancer models.
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Date
2015-03-24
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Article
Citation
First-in-human pharmacokinetic and pharmacodynamic study of the dual m-TORC 1/2 inhibitor, AZD2014. 2015: Clin Cancer Res