Loading...
Estimation of renal function -- what is appropriate in cancer patients?
Barraclough, Lisa H Field, Catherine Wieringa, Gilbert E Swindell, Ric Livsey, Jacqueline E Davidson, Susan E
Barraclough, Lisa H
Field, Catherine
Wieringa, Gilbert E
Swindell, Ric
Livsey, Jacqueline E
Davidson, Susan E
Citations
Altmetric:
Abstract
AIMS: To compare the accuracy of renal assessment in patients with cancer using radioisotope glomerular filtration rate (GFR), urine collection for creatinine clearance, Cockroft-Gault, Modification of Diet in Renal Disease (MDRD) and Wright formulae. MATERIALS AND METHODS: Measurements of isotope GFR from 367 patients were compared with estimates from the described methods (Cockroft-Gault, MDRD, Wright). An analysis including a further 252 patients with an isotope GFR < or = 50 ml/min was also carried out. RESULTS: The Wright formula was the most accurate form of estimating renal function for the first study group. The formulae were similar in accuracy in the second study group. CONCLUSIONS: The Wright formula is the most accurate form of estimation of renal function in comparison with the isotope GFR for cancer patients. When there is a large proportion of patients with a low isotope GFR (< or = 50 ml/min), the formulae have similar accuracy.
Description
Date
2008-12
Publisher
Keywords
GFR
Renal Cancer
Renal Function Assessment
Cancer
Renal Cancer
Renal Function Assessment
Cancer
Type
Article
Citation
Estimation of renal function -- what is appropriate in cancer patients? 2008, 20 (10):721-6 Clin Oncol (R Coll Radiol)