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Nitrogen analogues of haematoporphyrin and haematoporphyrin derivative.

Forbes, E
; 
Keir, W F
; 
MacLennan, A H
; 
Moore, James V
; 
Truscott, T G
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Abstract
The preparation of a number of amines related to haematoporphyrin (HP) and haematoporphyrin derivative (HPD) have been studied and their composition and structure discussed through examination of their 1H, 13C NMR and mass spectral data and other physical properties. In vitro biological studies have been carried out and have shown these amines to have a similar photodynamic efficiency to that of HPD. One of these showed cytotoxic properties at exceptionally low light energy levels.
Authors
Forbes, E
Keir, W F
MacLennan, A H
Moore, James V
Truscott, T G
Affiliation
Department of Chemistry and Chemical Engineering, University of Paisley, Renfrewshire, Scotland, UK.
Description
Date
1992-12-24
Publisher
Collections
All Paterson Institute for Cancer Research
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Keywords
Haematoporphyrin Derivative
Haematoporphyrin Photoradiation
Haematoporphyrins
Cancer
Cultured Tumour Cells
Type
Article
Citation
Nitrogen analogues of haematoporphyrin and haematoporphyrin derivative. 1992, 67 (2-3):175-85 Cancer Lett.
Journal Title
Journal ISSN
Volume Title
URI
http://hdl.handle.net/10541/108843
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