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The suitability of carboplatin solutions for 14-day continuous infusion by ambulatory pump: an HPLC-dynamic FAB study.
Hadfield, John A McGown, Alan T Dawson, Martin J Thatcher, Nick Fox, Brian W
Hadfield, John A
McGown, Alan T
Dawson, Martin J
Thatcher, Nick
Fox, Brian W
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Abstract
The stability of aqueous carboplatin solutions over 14 days has been studied at 37 and 60 degrees C. High-performance liquid chromatography and dynamic FAB mass spectrometry studies have shown that carboplatin solutions were stable at 37 degrees C but degraded at 60 degrees C. Fluid loss through evaporation was significant at the higher temperature.
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Date
1993-08
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Article
Citation
The suitability of carboplatin solutions for 14-day continuous infusion by ambulatory pump: an HPLC-dynamic FAB study. 1993, 11 (8):723-7 J Pharm Biomed Anal