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Data-driven mapping of hypoxia-related tumor heterogeneity using DCE-MRI and OE-MRI.
Featherstone, Adam K O'Connor, James P B Little, R Watson, Y Cheung, S Babur, M Williams, Kaye J Matthews, Julian C Parker, Geoff J M
Featherstone, Adam K
O'Connor, James P B
Little, R
Watson, Y
Cheung, S
Babur, M
Williams, Kaye J
Matthews, Julian C
Parker, Geoff J M
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Abstract
Previous work has shown that combining dynamic contrast-enhanced (DCE)-MRI and oxygen-enhanced (OE)-MRI binary enhancement maps can identify tumor hypoxia. The current work proposes a novel, data-driven method for mapping tissue oxygenation and perfusion heterogeneity, based on clustering DCE/OE-MRI data.
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2017-08-30
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Data-driven mapping of hypoxia-related tumor heterogeneity using DCE-MRI and OE-MRI. 2017 Magn Reson Med