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PARG inhibitors exhibit synthetic lethality with XRCC1 deficiency and a cellular mechanism of action that is distinct from PARP inhibition

Martin, Leenus
Cheng, Tzuling
James, Dominic I
Begum, Habiba
Smith, Kate M
Jordan, Allan M
Waddell, Ian D
Vaidya, Kedar
Fischer, Marcus
Yao, Bing
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Meetings and Proceedings
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Martin L, Cheng T, James DI, Begum H, Smith KM, Jordan A, et al. Abstract 1943: PARG inhibitors exhibit synthetic lethality with XRCC1 deficiency and a cellular mechanism of action that is distinct from PARP inhibition. Cancer Res. 2018;78(13):1943.
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