PARG inhibitors exhibit synthetic lethality with XRCC1 deficiency and a cellular mechanism of action that is distinct from PARP inhibition
Martin, Leenus ; Cheng, Tzuling ; James, Dominic I ; Begum, Habiba ; Smith, Kate M ; Jordan, Allan M ; Waddell, Ian D ; Vaidya, Kedar ; Fischer, Marcus ; Yao, Bing ... show 10 more
Martin, Leenus
Cheng, Tzuling
James, Dominic I
Begum, Habiba
Smith, Kate M
Jordan, Allan M
Waddell, Ian D
Vaidya, Kedar
Fischer, Marcus
Yao, Bing
Citations
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Abstract
Authors
Martin, Leenus
Cheng, Tzuling
James, Dominic I
Begum, Habiba
Smith, Kate M
Jordan, Allan M
Waddell, Ian D
Vaidya, Kedar
Fischer, Marcus
Yao, Bing
Drummond, Jason
Cleary, Leah
Martinez, Ruben
Sutton, James
Ravindran, Nandini
Joseph, James
Venetsanakos, Eleni
Dillon, Michael
Hager, Jeffrey H
Belmont, Lisa D
Cheng, Tzuling
James, Dominic I
Begum, Habiba
Smith, Kate M
Jordan, Allan M
Waddell, Ian D
Vaidya, Kedar
Fischer, Marcus
Yao, Bing
Drummond, Jason
Cleary, Leah
Martinez, Ruben
Sutton, James
Ravindran, Nandini
Joseph, James
Venetsanakos, Eleni
Dillon, Michael
Hager, Jeffrey H
Belmont, Lisa D
Description
Date
2018
Publisher
Collections
Keywords
Type
Meetings and Proceedings
Citation
Martin L, Cheng T, James DI, Begum H, Smith KM, Jordan A, et al. Abstract 1943: PARG inhibitors exhibit synthetic lethality with XRCC1 deficiency and a cellular mechanism of action that is distinct from PARP inhibition. Cancer Res. 2018;78(13):1943.