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Cysteine cathepsin protease inhibition: an update on its diagnostic, prognostic and therapeutic potential in cancer
Soond, SM Kozhevnikova, MV Townsend, Paul A Zamyatnin, AA
Soond, SM
Kozhevnikova, MV
Townsend, Paul A
Zamyatnin, AA
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Abstract
In keeping with recent developments in basic research; the importance of the Cathepsins as targets in cancer therapy have taken on increasing importance and given rise to a number of key areas of interest in the clinical setting. In keeping with driving basic research in this area in a translational direction; recent findings have given rise to a number of exciting developments in the areas of cancer diagnosis; prognosis and therapeutic development. As a fast-moving area of research; the focus of this review brings together the latest findings and highlights the translational significance of these developments.
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Date
2019
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Citation
Soond SM, Kozhevnikova MV, Townsend PA, Zamyatnin AA, Jr. Cysteine cathepsin protease inhibition: an update on its diagnostic, prognostic and therapeutic potential in cancer. Pharmaceuticals (Basel). 2019 Jun 11;12(2).