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Implication of protein aromatic amino acids in concanavalin A-carbohydrate interactions. A radiolytic study.

Davies, J Vernon
Moore, J S
Mudher, S
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Abstract
Pulse radiolysis and 60Co gamma-radiolysis have been used to study the effects of ionizing radiation on the glycogen-precipitating activity of the protein concanavalin A. Both eaq- and OH. react extremely rapidly with the protein and contribute to the observed loss of concanavalin A activity. Evidence is also presented that (Br)2-. and (SCN)2-. react with with tyrosine and tryptophan residues in concanavalin A, which is also accompanied by loss of glycogen precipitation activity.
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1978-01
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Article
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Implication of protein aromatic amino acids in concanavalin A-carbohydrate interactions. A radiolytic study. 1978, 33 (1):11-9 Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med.
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