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Abstract
Platform trials are adaptive randomised controlled trials that address multiple questions using a single protocol, which reduces the time taken to reach a meaningful trial endpoint. This mini review provides a description of how to conceive, design, and carry out a platform trial in urology, using experience gained in the STAMPEDE trial. PATIENT SUMMARY: Clinical trials to test how well a new drug or treatment works can take a long time before meaningful results can be assessed. Trials with a platform design can test multiple treatments using just one protocol and control, which reduces the time taken to reach a trial endpoint.
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Description
Date
2023
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Keywords
Type
Article
Citation
Clarke NW, James ND. How to Compose Platform Trials. Eur Urol Focus. 2023 Nov 2. PubMed PMID: 37925327. Epub 2023/11/05. eng.