Re-irradiation of rat tails to necrosis at six months after treatment with a "tolerance" dose of x rays or neutrons.
Hendry, Jolyon H Rosenberg, I Greene, D Stewart, J
Hendry, Jolyon H
Rosenberg, I
Greene, D
Stewart, J
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Abstract
Rat tails were re-irradiated to necrosis levels at about six months after various fractionated treatments with 290 kV X rays or 14 MeV neutrons. The X ray dose required to produce necrosis in half of a group of tails (ND50), which had been heavily X-irradiated six months before, was 91+/-4% of the ND50 for aged controls. After prior neutron-irradiation, however, this value was 87+/-4% (neutrons in second treatment) or 75+/-5% (X rays in second course). The "effective" oxygenation of mouse tails at this time after X-irradiation was similar to that of controls; thus these percentage dose values indicate the remarkable tolerance of this organized tissue to a second course of X-irradiation, and the presence of more residual injury in neutron-irradiated tissues.
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Date
1977-08
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Re-irradiation of rat tails to necrosis at six months after treatment with a "tolerance" dose of x rays or neutrons. 1977, 50 (596):567-72 Br J Radiol