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Routine measurement of plasma chromogranin B has limited clinical utility in the management of patients with neuroendocrine tumours.

Monaghan, Phillip J
Lamarca, Angela
Mansoor, Was
Trainer, Peter J
Darby, D
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Abstract
Chromogranin-A (CgA) and -B (CgB) are markers for monitoring disease status in patients with gastroenteropancreatic neuroendocrine tumours (NETs). These are specialised diagnostic tests often necessitating referral of specimens to a supra-regional assay service (SAS) laboratory for analysis. The aim of this audit was to assess if measurement of either plasma CgA or CgB alone provides sufficient clinical information in comparison to the current practice of measuring both markers together.
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2015-11-26
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Routine measurement of plasma chromogranin B has limited clinical utility in the management of patients with neuroendocrine tumours. 2015: Clin.Endocrinol
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