Dimethanesulphonate esters in receptor mapping studies. 2. Antitumour activities of alkyl and alkoxy dimethanesulphonates substituted on a benzene nucleus.
Hadfield, John A ; Fox, Brian W ; Caffrey, Robert
Hadfield, John A
Fox, Brian W
Caffrey, Robert
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Abstract
The antitumour activities of 15 novel aromatic dimethanesulphonate esters were studied. Several alkyl and alkoxy compounds have shown good antitumour activity whilst similar isomers have proved ineffective as antitumour agents. These differences in activity have been correlated with the length of the sidechain substituents and their relative flexibilities.
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Date
1992-06
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Article
Citation
Dimethanesulphonate esters in receptor mapping studies. 2. Antitumour activities of alkyl and alkoxy dimethanesulphonates substituted on a benzene nucleus. 1992, 7 (3):263-75 Anticancer Drug Des.