Suitability of cisplatin solutions for 14-day continuous infusion by ambulatory pump.
Hrubisko, M McGown, Alan T Prendiville, Joseph A Radford, John A Thatcher, Nick Fox, Brian W
Hrubisko, M
McGown, Alan T
Prendiville, Joseph A
Radford, John A
Thatcher, Nick
Fox, Brian W
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Abstract
The stability of cisplatin (DDP) solutions (1 and 1.6 mg/ml in saline-mannitol) in plastic infusion bags was studied for up to 14 days at 25 degrees C, 37 degrees C and 60 degrees C. Small changes in the solution were observed, but no evidence of any decomposition product was seen. Some precipitation of DDP was seen in the 1.6-mg/ml solution at the lower temperatures. Fluid loss from the bags was significant at the higher temperatures.
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Date
1992
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Article
Citation
Suitability of cisplatin solutions for 14-day continuous infusion by ambulatory pump. 1992, 29 (3):252-5 Cancer Chemother Pharmacol