Primary small cell neuroendocrine carcinoma of the kidney.
Morgan, K G Banerjee, Saumitra S Eyden, Brian P Barnard, R J
Morgan, K G
Banerjee, Saumitra S
Eyden, Brian P
Barnard, R J
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Abstract
The histological, immunohistochemical, and ultrastructural features of a primary small cell neuroendocrine carcinoma of the renal parenchyma are described. Tumor cells were positive for cytokeratin, neuron-specific enolase, and Leu 7, but Grimelius- and chromogranin-negative. They also exhibited positivity with anti-MIC2 antibody. By electron microscopy, tonofibrils, primitive desmosomes, and dense-core granules with a neuroendocrine appearance were present. This is only the 7th recorded example of such a tumor at this site, which showed an aggressive course characterized by widespread bony metastases.
Description
Date
2010-04-07T15:30:09Z
Publisher
Collections
Keywords
Kidney Cancer
Type
Article
Citation
Primary small cell neuroendocrine carcinoma of the kidney., 20 (2):141-4 Ultrastruct Pathol