A randomised study evaluating the use of pyridoxine to avoid capecitabine dose modifications.
Corrie, P Bulusu, R Wilson, C Armstrong, G Bond, S Hardy, R Lao-Sirieix, S Parashar, D Ahmad, A Daniel, F
Corrie, P
Bulusu, R
Wilson, C
Armstrong, G
Bond, S
Hardy, R
Lao-Sirieix, S
Parashar, D
Ahmad, A
Daniel, F
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Abstract
Pyridoxine is frequently used to treat capecitabine-induced hand-foot syndrome (HFS), although the evidence of benefit is lacking. We performed a randomised placebo-controlled trial to determine whether pyridoxine could avoid the need for capecitabine dose modifications and improve outcomes.
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Date
2012-08-07
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Article
Citation
A randomised study evaluating the use of pyridoxine to avoid capecitabine dose modifications. 2012, 107 (4):585-7 Br J Cancer