Repeated investigations of cyclophosphamide disposition in myeloma patients receiving intermittent chemotherapy.
Edwards, G Calvert, R T Crowther, Derek Bramwell, Vivien H C Scarffe, J Howard
Edwards, G
Calvert, R T
Crowther, Derek
Bramwell, Vivien H C
Scarffe, J Howard
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Abstract
1 The disposition of cyclophosphamide was investigated in a group of myeloma patients. 2 Marked changes in clearance and volume of distribution of cyclophosphamide occurred between investigations. 3 The observed changes in disposition did not correlate with biochemical estimates of renal and hepatic function or plasma protein status.
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Date
1980-09
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Collections
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Article
Citation
Repeated investigations of cyclophosphamide disposition in myeloma patients receiving intermittent chemotherapy. 1980, 10 (3):281-5 Br J Clin Pharmacol