Telotristat etiprate for carcinoid syndrome: a single-arm, multicenter trial.
Pavel, M Hörsch, D Caplin, M Ramage, J Seufferlein, T Banks, P Lapuerta, P Sands, A Zambrowicz, B
Pavel, M
Hörsch, D
Caplin, M
Ramage, J
Seufferlein, T
Banks, P
Lapuerta, P
Sands, A
Zambrowicz, B
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Abstract
Carcinoid syndrome (CS) is associated with elevated serotonin, diarrhea, flushing, and increased risk of valvular heart disease. Many patients respond to somatostatin analogs initially, but response diminishes in most patients. Additional options are needed.
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Date
2015-04
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Article
Citation
Telotristat etiprate for carcinoid syndrome: a single-arm, multicenter trial. 2015, 100 (4):1511-9 J Clin Endocrinol Metab