A structure resembling basal/external lamina on the surface of plasma cells, and a discussion on intercellular contacts between hemolymphoid cells.
Eyden, Brian P
Eyden, Brian P
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Abstract
Basal/external lamina is not found over plasma cells or other hemolymphoid cells, and the feature can have diagnostic value in distinguishing the neoplastic counterparts of such cells from epithelium, endothelium, mesothelium, and so on, which do have this feature. In this paper, a material ultrastructurally indistinguishable from basal or external lamina is reported on reactive plasma cells found in a fibrous pseudotumor, intralobular stroma of normal breast, tumor stroma of squamous cell carcinoma, and submucosa of normal human small intestine. It was focal, followed the contours of the cell-surface membrane, was lightly textured, 40-80 nm thick, and separated from the plasma cell surface membrane by a clear space resembling a lamina lucida. Its function remains uncertain, although it may implement adhesion to other cells, as part of the immune functions that plasma cells and other hemolymphoid cells perform in the gut, for example, and elsewhere.
Authors
Description
Date
2009
Publisher
Collections
Keywords
Basal Lamina
Immune Function
Ultrastructure
Tumour
Immune Function
Ultrastructure
Tumour
Type
Article
Citation
A structure resembling basal/external lamina on the surface of plasma cells, and a discussion on intercellular contacts between hemolymphoid cells., 33 (1):16-20 Ultrastruct Pathol