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Singlet oxygen and superoxide characteristics of a series of novel asymmetric photosensitizers.
Haylett, Ann K ; McNair, Fiona I ; McGarvey, D ; Dodd, Nicholas J F ; Forbes, E ; Truscott, T G ; Moore, James V
Haylett, Ann K
McNair, Fiona I
McGarvey, D
Dodd, Nicholas J F
Forbes, E
Truscott, T G
Moore, James V
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Abstract
The singlet oxygen quantum yields and superoxide quantum yields for a series of novel compounds based on an asymmetrical protoporphyrin molecule have been examined. Electron spin resonance was used to measure superoxide yield and time resolved luminescence for singlet oxygen. A comparison between these results and previously published cell survival data was carried out. A broad association was found between singlet oxygen quantum yield and clonogenic cell kill.
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Date
1997-01-30
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Article
Citation
Singlet oxygen and superoxide characteristics of a series of novel asymmetric photosensitizers. 1997, 112 (2):233-8 Cancer Lett.