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Using prior information from the medical literature in GWAS of oral cancer identifies novel susceptibility variant on chromosome 4--the AdAPT method.

Johansson, M
; 
Roberts, A
; 
Chen, D
; 
Li, Yaoyong
; 
Delahaye-Sourdeix, M
; 
Aswani, N
; 
Greenwood, M
; 
Benhamou, S
; 
Lagiou, P
; 
Holcátová, I
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Abstract
Genome-wide association studies (GWAS) require large sample sizes to obtain adequate statistical power, but it may be possible to increase the power by incorporating complementary data. In this study we investigated the feasibility of automatically retrieving information from the medical literature and leveraging this information in GWAS.
Authors
Johansson, M
Roberts, A
Chen, D
Li, Yaoyong
Delahaye-Sourdeix, M
Aswani, N
Greenwood, M
Benhamou, S
Lagiou, P
Holcátová, I
Richiardi, L
Kjaerheim, K
Agudo, A
Castellsagué, X
Macfarlane, T
Barzan, L
Canova, C
Thakker, N
Conway, D
Znaor, A
Healy, C
Ahrens, W
Zaridze, D
Szeszenia-Dabrowska, N
Lissowska, J
Fabiánová, E
Mates, I
Bencko, V
Foretova, L
Janout, V
Curado, M
Koifman, S
Menezes,
Wünsch-Filho, V
Eluf-Neto, J
Boffetta, P
Franceschi, S
Herrero, R
Fernandez Garrote, L
Talamini, R
Boccia, S
Galan, P
Vatten, L
Thomson, P
Zelenika, D
Lathrop, M
Byrnes, G
Cunningham, H
Brennan, Paul
Wakefield, J
McKay, J
Affiliation
Section of Genetics, International Agency for Research on Cancer (IARC), Lyon, France.
Description
Date
2012
Publisher
Collections
All Paterson Institute for Cancer Research
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Keywords
Type
Article
Citation
Using prior information from the medical literature in GWAS of oral cancer identifies novel susceptibility variant on chromosome 4--the AdAPT method. 2012, 7 (5):e36888 PLoS ONE
Journal Title
Journal ISSN
Volume Title
URI
http://hdl.handle.net/10541/240454
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